Nitazoxanide
Generic name: nitazoxanide [ NYE-ta-ZOX-a-nide ]
Brand name: Alinia
Dosage forms: oral powder for reconstitution (100 mg/5 mL), oral tablet (500 mg)
Drug class: Amebicides
What is nitazoxanide?
Nitazoxanide is an antiprotozoal medicine that treats infections caused by protozoa (single-cell parasites that live in moist places such as lakes, streams, and soil).
Nitazoxanide is used to treat diarrhea caused by Giardia or Cryptosporidium. These conditions are sometimes called "Traveler's diarrhea." Nitazoxanide is used in adults and children who are at least 1 year old.
Nitazoxanide may also be used for purposes not listed in this medication guide.
Nitazoxanide side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Common side effects of nitazoxanide may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Warnings
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
You should not use nitazoxanide if you are allergic to it.
To make sure nitazoxanide is safe for you, tell your doctor if you have:
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liver or kidney disease;
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HIV or AIDS; or
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a weak immune system.
The tablet form of nitazoxanide should not be given to a child younger than 12 years old. Children ages 1 to 11 years should use only the oral suspension (liquid) form of nitazoxanide.
Nitazoxanide is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant.
It is not known whether nitazoxanide passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
How should I take nitazoxanide?
Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Take nitazoxanide with food.
Nitazoxanide is usually taken once every 12 hours for 3 days. Follow your doctor's dosing instructions very carefully.
Shake the oral suspension (liquid) well just before you measure a dose. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use. Throw away any unused liquid after 7 days.
Nitazoxanide dosing information
Usual Adult Dose for Cryptosporidiosis:
500 mg orally every 12 hours for 3 days
Use: For the treatment of diarrhea due to Giardia lamblia or Cryptosporidium parvum
Usual Adult Dose for Giardiasis:
500 mg orally every 12 hours for 3 days
Use: For the treatment of diarrhea due to Giardia lamblia or Cryptosporidium parvum
Usual Pediatric Dose for Cryptosporidiosis:
1 to 3 years: 100 mg orally every 12 hours
4 to 11 years: 200 mg orally every 12 hours
12 years or older: 500 mg orally every 12 hours
Duration of Therapy: 3 days
Use: For the treatment of diarrhea due to G lamblia or C parvum
Usual Pediatric Dose for Giardiasis:
1 to 3 years: 100 mg orally every 12 hours
4 to 11 years: 200 mg orally every 12 hours
12 years or older: 500 mg orally every 12 hours
Duration of Therapy: 3 days
Use: For the treatment of diarrhea due to G lamblia or C parvum
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking nitazoxanide?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
What other drugs will affect nitazoxanide?
Other drugs may interact with nitazoxanide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
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Further information
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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